Diet studies norfolk virginia volunteers
Methods A total of 412 participants were randomly assigned to eat either a control diet typical of intake in the United States or the DASH diet. The primary end point was the rate of major cardiovascular events (myocardial infarction, stroke, or death from cardiovascular causes). , Laura P. 1 mm Hg (P Full Text of Results. D. , Marlene M. , Pao-Hwa Lin, Ph. We conducted a randomized trial of this diet pattern for the primary prevention of cardiovascular events. Simons-Morton, M. , William M. 8 years. , Mikel Aickin, Ph. Most-Windhauser, Ph. D. D. D. A primary end-point event occurred in 288 participants. Media in This Article Figure 1 The Effect on Systolic Blood Pressure (Panel A) and Diastolic Blood Pressure (Panel B) of Reduced Sodium Intake and the DASH Diet. Svetkey, M. , Ph. The two Mediterranean-diet groups had good adherence to the intervention, according to self-reported intake and biomarker analyses. D. Detailed enrollment criteria are provided in the Supplementary Appendix, available at NEJM. Abstract Background Observational cohort studies and a secondary prevention trial have shown an inverse association between adherence to the Mediterranean diet and cardiovascular risk. Results Reducing the sodium intake from the high to the intermediate level reduced the systolic blood pressure by 2. Original Article Effects on Blood Pressure of Reduced Dietary Sodium and the Dietary Approaches to Stop Hypertension (DASH) Diet Frank M.
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Details of the trial design are provided elsewhere. Within the assigned diet, participants ate foods with high, intermediate, and low levels of sodium for 30 consecutive days each, in random order. On the basis of the results of an interim analysis, the trial was stopped after a median follow-up of 4. , Michael A. Beginning on October 1, 2003, participants were randomly assigned, in a 1:1:1 ratio, to one of three dietary intervention groups: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with nuts, or a control diet. , Thomas J. Moore, M. Conclusions The reduction of sodium intake to levels below the current recommendation of 100 mmol per day and the DASH diet both lower blood pressure substantially, with greater effects in combination than singly. Figure 2 The Effect on Systolic Blood Pressure of Dietary Sodium Intake during the Control Diet (Panel A) and the DASH Diet (Panel B), According to Subgroup. , Njeri Karanja, Ph. D. Participants received quarterly individual and group educational sessions and, depending on group assignment, free provision of extra-virgin olive oil, mixed nuts, or small nonfood gifts. D. org. Long-term health benefits will depend on the ability of people to make long-lasting dietary changes and the increased availability of lower-sodium foods. We studied the effect of different levels of dietary sodium, in conjunction with the Dietary Approaches to Stop Hypertension (DASH) diet, which is rich in vegetables, fruits, and low-fat dairy products, in persons with and in those without hypertension. D. Abstract Background The effect of dietary composition on blood pressure is a subject of public health importance. None of the sponsors had any role in the trial design, data analysis, or reporting of the results. 10-12 The trial was designed and conducted by the authors, and the protocol was approved by the institutional review boards at all study locations. Sacks, M. Full Text of Methods. All participants provided written informed consent. D. Methods In a multicenter trial in Spain, we randomly assigned participants who were at high cardiovascular risk, but with no cardiovascular disease at enrollment, to one of three diets: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with mixed nuts, or a control diet (advice to reduce dietary fat).
